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Akynzeo and Severe hepatic impairment

Result of checking the interaction of drug Akynzeo and disease Severe hepatic impairment for safety when used together.

Check result:

Akynzeo <> Severe hepatic impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Limited data are available with fosnetupitant (only available in combination with palonosetron in the US) in patients with severe hepatic impairment (Child-Pugh score greater than 9), therefore, its use should be avoided in these patients. No dosage adjustment is necessary for patients with mild to moderate hepatic impairment (Child-Pugh score 5 to 8).

Akynzeo

Generic Name: netupitant / palonosetron

Brand Name: Akynzeo

Synonyms: n.a.

What is Akynzeo?