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Disulfiram and Hepatotoxicity

Result of checking the interaction of drug Disulfiram and disease Hepatotoxicity for safety when used together.

Check result:

Disulfiram <> Hepatotoxicity

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Hepatic toxicity, hepatitis, and hepatic failure resulting in transplantation or death have been reported with the use of disulfiram. Hepatic toxicity has occurred in patient with and without prior history of abnormal liver function. Extreme caution and close monitoring is advised if used in patients with liver impairment. Baseline and liver tests are suggested in all patients to detect any hepatic abnormalities. Patients should be advised to immediately notify their health provider if any symptoms of hepatitis occur (weakness, fatigue, anorexia, nausea, vomiting, jaundice, or dark urine).

Disulfiram

Generic Name: disulfiram

Brand Name: Antabuse

Synonyms: n.a.

What is Disulfiram?