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DocuSol Plus Mini-Enema and Methemoglobinemia

Result of checking the interaction of drug DocuSol Plus Mini-Enema and disease Methemoglobinemia for safety when used together.

Check result:

DocuSol Plus Mini-Enema <> Methemoglobinemia

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Rarely, benzocaine has induced methemoglobinemia resulting in respiratory distress and cyanosis. Therapy with benzocaine should be administered cautiously to patients with or predisposed to methemoglobinemia. If life-threatening or severe methemoglobinemia develops, methylene blue infused at a dosage of 1 to 2 mg/kg body weight will rapidly reverse or improve the condition except in G-6-PD-deficient patients.

References:

"Product Information. Americaine (benzocaine topical)." Novartis Consumer Health, Summit, NJ.
"Product Information. Americaine Otic (benzocaine otic)." Medeva Pharmaceuticals, Rochester, NY.

DocuSol Plus Mini-Enema

Generic Name: benzocaine / docusate topical

Brand Name: DocuSol Plus Mini-Enema

Synonyms: Benzocaine and Docusate

What is DocuSol Plus Mini-Enema?