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Endrate and Renal dysfunction

Result of checking the interaction of drug Endrate and disease Renal dysfunction for safety when used together.

Check result:
Endrate <> Renal dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of disodium EDTA is contraindicated in patients with anuria and severe renal dysfunction. Dose-related nephrotoxicity (usually reversible) associated with EDTA has included polyuria, dysuria, oliguria, proteinuria, cast and cells in urine, renal insufficiency/failure, and rarely, acute tubular necrosis. EDTA disodium is eliminated by the kidney primarily chelated to calcium. Impaired renal function decreases the elimination of EDTA and may increase its nephrotoxicity.

References:
  • "Product Information. Disotate (edetate disodium (EDTA).)." Abbott Pharmaceutical, Abbott Park, IL.
Endrate

Generic Name: edetate disodium (edta)

Brand Name:

Synonyms: n.a.

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