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Ethambutol and Hyperuricemia

Result of checking the interaction of drug Ethambutol and disease Hyperuricemia for safety when used together.

Check result:

Ethambutol <> Hyperuricemia

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Ethambutol may commonly cause hyperuricemia, which has been reported in up to two-thirds of treated patients. Occasionally, it has led to joint arthralgias and gouty arthritis after 1 to 2 months of therapy. Serum uric acid levels should be monitored in patients with preexisting hyperuricemia or gout during ethambutol therapy, and appropriate measures (e.g., administration of uricosuric agents) taken to prevent the development or exacerbation of gout.

References:

Khanna BK "Acute gouty arthritis following ethambutol therapy." Br J Dis Chest 74 (1980): 409-10
Narang RK, Agarwal MC, Raina AK, et al "Hyperuricaemia induced by ethambutol." Br J Dis Chest 77 (1983): 403-6
"Product Information. Myambutol (ethambutol)." Lederle Laboratories, Wayne, NJ.
Postlethwaite AE, Bartel AG, Kelley WN "Hyperuricemia due to ethambutol." N Engl J Med 286 (1972): 761-2
Khanna BK, Gupta VP, Singh MP "Ethambutol-induced hyperuricaemia." Tubercle 65 (1984): 195-9

Ethambutol

Generic Name: ethambutol

Brand Name: Myambutol

Synonyms: n.a.

What is Ethambutol?