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Ethyol and Hypotension

Generic Name: amifostine
Dosage Forms: injection, powder, lyophilized, for solution
Other Brand Names: Ethyol

Result of checking the interaction of drug Ethyol and disease Hypotension for safety when used together.

Check result:

Ethyol <> Hypotension

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Patients who are hypotensive or in state of dehydration, or those that are unable to discontinue antihypertensive treatment 24 hours prior to amifostine administration should not receive amifostine. Transient hypotensive episodes have occurred in 62% of patients receiving amifostine. Three percent of patients required discontinuation of amifostine. Therapy with amifostine should be administered cautiously in patients adversely affected by hypotensive effects such as cardiovascular conditions of arrhythmia, angina, or CHF or cerebrovascular conditions of or history of stroke or ischemic attacks. Clinical monitoring of blood pressure is necessary.

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