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Evenity and Osteonecrosis of the jaw

Result of checking the interaction of drug Evenity and disease Osteonecrosis of the jaw for safety when used together.

Check result:

Evenity <> Osteonecrosis of the jaw

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Osteonecrosis of the jaw (ONJ), has been reported in patients receiving romosozumab. A routine oral examination should be performed prior to initiation of treatment. Risk factors for ONJ include cancer, radiotherapy, poor oral hygiene, preexisting dental disease or infection, anemia, and coagulopathy, and concomitant use of other drugs associated with ONJ (e.g., chemotherapy, bisphosphonates). Patients requiring invasive dental procedures, require clinical judgment of the treating physician and/or oral surgeon to guide the management plan based on benefit-risk assessment. Patients who are suspected of having or who develop ONJ while on romosozumab treatment, should receive care by a dentist or an oral surgeon. In these patients, dental surgery to treat ONJ may exacerbate the condition. Discontinuation of treatment should be considered based on benefit-risk assessment.

Evenity

Generic Name: romosozumab

Brand Name: Evenity

Synonyms: Evenity Injection

What is Evenity?