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Fosamax (Alendronate Oral Solution) and Renal dysfunction

Generic Name: alendronate
Dosage Forms: tablet
Other Brand Names: Binosto , Fosamax

Result of checking the interaction of drug Fosamax (Alendronate Oral Solution) and disease Renal dysfunction for safety when used together.

Check result:

Fosamax (Alendronate Oral Solution) <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Alendronate is primarily eliminated by the kidney. In healthy controls, drug that is not deposited in bone is rapidly excreted in the urine. Although clinical information is not available, animal studies suggest reduced drug clearance in renal failure. Alendronate is not recommended for use in patients with creatinine clearance less than 35 mL/min due to a lack of clinical experience in this setting. No dosage adjustment is necessary in patients with mild to moderate renal impairment (CrCl >= 35 mL/min).

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