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Gefitinib and Renal dysfunction

Result of checking the interaction of drug Gefitinib and disease Renal dysfunction for safety when used together.

Check result:
Gefitinib <> Renal dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Less than four percent (<4%) of gefitinib and its metabolites are excreted via the kidney. Population pharmacokinetic analyses suggest that creatinine clearance (above 20 mL/min) has no clinically meaningful effect on predicted steady state trough concentration of gefitinib. No clinical studies were conducted with gefitinib in patients with severe renal impairment.

Gefitinib

Generic Name: gefitinib

Brand Name: Iressa

Synonyms: n.a.

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