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Hexalen and Neurologic dysfunction

Generic Name: altretamine
Dosage Forms: capsule
Other Brand Names: Hexalen

Result of checking the interaction of drug Hexalen and disease Neurologic dysfunction for safety when used together.

Check result:

Hexalen <> Neurologic dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of altretamine is contraindicated in patients with severe neurological impairment. Peripheral neuropathy as well as central nervous system symptoms of ataxia, vertigo, mood disorders, and disorders of consciousness has been noted during administration of altretamine. However, altretamine has been administered safely to patients with cisplatin-associated neuropathy and to patients administered other alkylating agents. Clinical monitoring of neurologic function should be performed prior to the initiation of each course of therapy and the dose adjusted as clinically indicated in these patients.

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