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Hexaminolevulinate and Cystitis

Result of checking the interaction of drug Hexaminolevulinate and disease Cystitis for safety when used together.

Check result:

Hexaminolevulinate <> Cystitis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Inflammation of the bladder may interfere with the diagnostic utility of hexaminolevulinate, which is an ester of the heme precursor, aminolevulinic acid. Following intravesical instillation of hexaminolevulinate, photoactive porphyrins are formed and accumulate intracellularly in bladder wall lesions. In humans, a higher degree of accumulation of porphyrins has been demonstrated in neoplastic or inflamed cells compared to normal bladder urothelium. As such, inflammation may lead to increased porphyrin buildup and higher risk of local toxicity upon illumination as well as false-positive fluorescence. Hexaminolevulinate should not be used in patients at high risk of bladder inflammation, such as those who received BCG immunotherapy or intravesical chemotherapy within the past 90 days. Widespread inflammation of the bladder should be excluded by cystoscopy before hexaminolevulinate is administered. If a widespread inflammation in the bladder becomes evident during white light inspection, the blue light inspection should be avoided.

Hexaminolevulinate

Generic Name: hexaminolevulinate

Brand Name: Cysview

Synonyms: n.a.

What is Hexaminolevulinate?